Klinik und Poliklinik für Kinder- und Jugendmedizin
 Universitätsmedizin Leipzig

Publications 1998-2018

 

 

2018

 

Geserick M, Vogel M, Gausche R, Spielau U, Lipek T, Keller E, Pfäffle RW, Kiess W, Körner A: Acceleration of BMI in Early Childhood and High Risk of Sustained Obesity. N Engl J Med 379:1303-12 (2018) 

 

Kalenda A, Landgraf K, Löffler D, Kovacs P, Kiess W, Körner A: The BDNF Val66Met polymorphism is associated with lower BMI, lower postprandial glucose levels and elevated carbohydrate intake in children and adolescents. Pediatr Obes 159-167 (2018)

 

Paech C, Anhalt M, Gebauer RA, Wagner F, Vogel M, Kirsten T, Weidenbach M, Kiess W, Dähnert I, Körner A: New normal limits for pediatric ECG in childhood obesity? Influence of childhood obesity on the ECG. Progr Pediatr Cardiol 48:119-123 (2018)

 

Junge KM, Leppert B, Jahreis S, Wissenbach DK, Feltens R, Grutzmann K, Thurmann L, Bauer T, Ishaque N, Schick M, Bewerunge-Hudler M, Roder S, Bauer M, Schulz A, Borte M, Landgraf K, Körner A, Kiess W, von Bergen M, Stangl GI, Trump S, Eils R, Polte T, Lehmann I: MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development. Clin Epigenetics 10:58 (2018)

 

Poulain T, Vogel M, Ludwig J, Gräfe N, Körner A, Kiess W: Reciprocal longitudinal associations between adolescents' media consumption and psychological health. Acad Pediatr (2018)

 

Käßner F, Sauer T, Penke M, Richter S, Landgraf K, Körner A, Kiess W, Händel N, Garten A: Simvastatin induces apoptosis in PTENhaploinsufficient lipoma cells. Int J Mol Med 41:(2018)

 

Händel N, Mothes T, Petroff D, Baber R, Jurkutat A, Flemming G, Kiess W, Hiemisch A, Körner A, Schlumberger W, Thiery J, Wolf J: Will the Real Coeliac Disease Please Stand Up? Coeliac Disease Prevalence in the German LIFE Child Study. J Pediatr Gastroenterol Nutr (2018)

 

Poulain T, Vogel M, Neef M, Abicht F, Hilbert A, Genuneit J, Körner A, Kiess W: Reciprocal Associations between Electronic Media Use and Behavioral Difficulties in Preschoolers. Int J Environ Res Public Health 15:(2018)

 

Rocha EPAA, Vogel M, Stanik J, Pietzner D, Willenberg A, Körner A, Kiess W: Serum Uric Acid Levels as an Indicator for Metabolically Unhealthy Obesity in Children and Adolescents. Horm Res Paediatr 31:1-9 (2018)

 

Kiess W, Penke M, Gesing J, Stoltze A, Körner A, Pfäffle R, Kratzsch J: Congenital hypothyroidism. J Pediatr Endocrinol Metab 31:595-596 (2018)

 

Erbs S, Broniecki H, Scheuermann K, Winzer E, Adam J, Spielau U, Woitek F, Sandri M, Zimmer M, Besler C, Kiess W, Linke A, Körner A, Mangner N: Impact of Weight Reduction During Adolescence on Parameters of Cardiac Geometry and Function in Obese Children. JACC Cardiovasc Imaging (2018) 

 

 

2017

 

Löffler D, Behrendt S, Creemers JW, Klammt J, Aust G, Stanik J, Kiess W, Kovacs P, Körner A: Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism. Mol Metab 6:295-305 (2017)

 

Schwartze JT, Landgraf K, Spielau U, Rockstroh D, Löffler D, Kratzsch J, Kiess W, Körner A: Adipocyte C1QTNF5 expression is BMI-dependently related to early adipose tissue dysfunction and systemic CTRP5 serum levels in obese children. Int J Obes (Lond) 41:955-963 (2017)

 

Gesing J, Scheuermann K, Wagner IV, Löffler D, Friebe D, Kiess W, Schuster V, Körner A: NAMPT serum levels are selectively elevated in acute infectious disease and in acute relapse of chronic inflammatory diseases in children. PLoS One 12:e0183027 (2017)

 

Stanik J, Kratzsch J, Landgraf K, Scheuermann K, Spielau U, Gausche R, Gasperikova D, Kiess W, Körner A: Concordance of bioactive vs. total immunoreactive serum leptin levels in children with severe early onset obesity. PLoS One 12:e0178107 (2017)  

 

Windholz J, Kovacs P, Schlicke M, Franke C, Mahajan A, Morris AP, Lemke JR, Klammt J, Kiess W, Schöneberg T, Pfäffle R, Körner A: Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children. J Pediatr Endocrinol Metab 30:507-515 (2017)

 

Junge J, Engel C, Vogel M, Naumann S, Löffler M, Thiery J, Kratzsch J, Kiess W, Körner A: Neck circumference is similarly predicting for impairment of glucose tolerance as classic anthropometric parameters among healthy and obese children and adolescents. J Pediatr Endocrinol Metab 30:643-650 (2017)  

 

Landgraf K, Schuster S, Meusel A, Garten A, Riemer T, Schleinitz D, Kiess W, Körner A: Short-term overfeeding of zebrafish with normal or high-fat diet as a model for the development of metabolically healthy versus unhealthy obesity. BMC Physiol 17:4 (2017)

 

Paech C, Liebold A, Gebauer RA, Wagner F, Vogel M, Kirsten T, Schauff M, Hiemisch A, Dähnert I, Kiess W, Körner A: Relative QT interval prolongation and electrical inhomogeneity of cardiac repolarization in childhood obesity. Progr Pediatr Cardiol 47:64-67 (2017)

 

Bussler S, Vogel M, Pietzner D, Harms K, Buzek T, Penke M, Händel N, Körner A, Baumann U, Kiess W, Flemming G: New pediatric percentiles of liver enzyme serum levels (ALT, AST, GGT): Effects of age, sex, BMI and pubertal stage. Hepatology (2017)

 

Wheeler E, Leong A, [62authors], Böttcher Y, [18authors], Kiess W, Kohara K, Kovacs P, [39authors], Tönjes A, [13authors], Stumvoll M, Watkins H, Aung T, Blüher M, [25authors], Körner A, [45authors], Barroso I, Meigs JB: Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Med 14:e1002383 (2017)

 

Poulain T, Baber R, Vogel M, Pietzner D, Kirsten T, Jurkutat A, Hiemisch A, Hilbert A, Kratzsch J, Thiery J, Fuchs M, Hirsch C, Rauscher FG, Loeffler M, Körner A, Nüchter M, Kiess W: The LIFE Child study: a population-based perinatal and pediatric cohort in Germany. Eur J Epidemiol 32:145-158 (2017)

 

Raulien N, Friedrich K, Strobel S, Rübner S, Baumann S, von Bergen M, Körner A, Krueger M, Rossol M, Wagner U: Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes. Front Immunol 8:609 (2017)

 

Hendricks AE, Bochukova EG, Marenne G, Keogh JM, Atanassova N, Bounds R, Wheeler E, Mistry V, Henning E, Körner A, Muddyman D, McCarthy S, Hinney A, Hebebrand J, Scott RA, Langenberg C, Wareham NJ, Surendran P, Howson JM, Butterworth AS, Danesh J, Nordestgaard BG, Nielsen SF, Afzal S, Papadia S, Ashford S, Garg S, Millhauser GL, Palomino RI, Kwasniewska A, Tachmazidou I, O'Rahilly S, Zeggini E, Barroso I, Farooqi IS: Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity. Sci Rep 7:4394 (2017)

 

Glock F, Vogel M, Naumann S, Kühnapfel A, Scholz M, Hiemisch A, Kirsten T, Rieger K, Körner A, Löffler M, Kiess W: Validity and intraobserver reliability of three-dimensional scanning compared with conventional anthropometry for children and adolescents from a population-based cohort study. Pediatr Res 81:736-744 (2017)

 

Loeffler-Wirth H, Vogel M, Kirsten T, Glock F, Poulain T, Körner A, Löffler M, Kiess W, Binder H: Body typing of children and adolescents using 3D-body scanning. PLoS One 12:e0186881 (2017)

 

Kess A, Spielau U, Beger C, Gausche R, Vogel M, Lipek T, Körner A, Pfäffle R, Kiess W: Further stabilization and even decrease in the prevalence rates of overweight and obesity in German children and adolescents from 2005 to 2015: a cross-sectional and trend analysis. Public Health Nutr 20:3075-3083 (2017)

 

Daxer J, Herttrich T, Zhao YY, Vogel M, Hiemisch A, Scheuermann K, Körner A, Kratzsch J, Kiess W, Quante M: Nocturnal levels of chemerin and progranulin in adolescents: influence of sex, body mass index, glucose metabolism and sleep. J Pediatr Endocrinol Metab 30:57-61 (2017)

 

Schreier M, Schwartze JT, Landgraf K, Scheuermann K, Erbs S, Herberth G, Pospisilik JA, Kratzsch J, Kiess W, Körner A: Osteopontin is BMI-independently Related to Early Endothelial Dysfunction in Children. J Clin Endocrinol Metab 101:4161-4169 (2016)

 

Löffler D, Landgraf K, Rockstroh D, Schwartze JT, Dunzendorfer H, Kiess W, Körner A: METRNL decreases during adipogenesis and inhibits adipocyte differentiation leading to adipocyte hypertrophy in humans. Int J Obes (Lond) 41:112-119 (2017)

 

Bussler S, Penke M, Flemming G, Elhassan YS, Kratzsch J, Sergeyev E, Lipek T, Vogel M, Spielau U, Körner A, de Giorgis T, Kiess W: Novel Insights in the Metabolic Syndrome in Childhood and Adolescence. Horm Res Paediatr 88:181-193 (2017)

 

Kiess W, Penke M, Kratzsch J, Vogel M, Kapellen T, Hoppmann J, Gesing J, Gausche R, Klamt S, Körner A, Pfäffle R: Pediatric endocrinology is pediatrics is public health. J Pediatr Endocrinol Metab 371-374 (2017) 

 

 

 

2016

 

Löffler D, Landgraf K, Körner A, Kratzsch J, Kirkby KC, Himmerich H: Modulation of triglyceride accumulation in adipocytes by psychopharmacological agents in vitro. J Psychiatr Res 72:37-42 (2016)

 

Ehehalt S, Wiegand S, Körner A, Schweizer R, Liesenkotter KP, Partsch CJ, Blumenstock G, Spielau U, Denzer C, Ranke MB, Neu A, Binder G, Wabitsch M, Kiess W, Reinehr T: Low association between fasting and OGTT stimulated glucose levels with HbA1c in overweight children and adolescents. Pediatr Diabetes 18:734-741 (2016)

 

Kiess W, Hoppmann J, Gesing J, Penke M, Körner A, Kratzsch J, Pfäffle R: Puberty - genes, environment and clinical issues. J Pediatr Endocrinol Metab 29:1229-1231 (2016)

Rockstroh D, Löffler D, Kiess W, Landgraf K, Körner A: Regulation of human adipogenesis by miR125b-5p. Adipocyte 5:283-297 (2016)

 

Landgraf K, Strobach A, Kiess W, Körner A: Loss of mtch2 function impairs early development of liver, intestine and visceral adipocytes in zebrafish larvae. FEBS Lett 590:2852-2861 (2016)

 

Landgraf K, Scholz M, Kovacs P, Kiess W, Körner A: FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children? PLoS One 11:e0161739 (2016)

 

Ehehalt S, Wiegand S, Körner A, Schweizer R, Liesenkotter KP, Partsch CJ, Blumenstock G, Spielau U, Denzer C, Ranke MB, Neu A, Binder G, Wabitsch M, Kiess W, Reinehr T: Diabetes screening in overweight and obese children and adolescents: choosing the right test. Eur J Pediatr 176:89-97 (2016)

 

Horikoshi M, [55authors], P K, [38authors], A T, M S, [3authors], W K, A K, [59uthors], MI M, Freathy RM: Genome-wide associations for birth weight and correlations with adult disease. Nature 538:248-252 (2016)

 

Dalgaard K, Landgraf K, Heyne S, Lempradl A, Longinotto J, Gossens K, Ruf M, Orthofer M, Strogantsev R, Selvaraj M, Lu TT, Casas E, Teperino R, Surani MA, Zvetkova I, Rimmington D, Tung YC, Lam B, Larder R, Yeo GS, O'Rahilly S, Vavouri T, Whitelaw E, Penninger JM, Jenuwein T, Cheung CL, Ferguson-Smith AC, Coll AP, Körner A, Pospisilik JA: Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity. Cell 164:353-364 (2016)

 

Felix JF, Bradfield JP, Monnereau C, van der Valk RJ, [47authors], Kiess W, [14authors], Pfäffle R, [33authors], Körner A, [9authors], Grant SF, Jaddoe VW, Early Growth Genetics C, Bone Mineral Density in Childhood Study BC: Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet 25:389-403 (2016)

 

Guiu-Jurado E, Unthan M, Bohler N, Kern M, Landgraf K, Dietrich A, Schleinitz D, Ruschke K, Klöting N, Fasshauer M, Tönjes A, Stumvoll M, Körner A, Kovacs P, Blüher M: Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots. Obesity (Silver Spring) 24:2092-2100 (2016)

 

Wagner IV, Flehmig G, Scheuermann K, Löffler D, Körner A, Kiess W, Stumvoll M, Dietrich A, Blüher M, Klöting N, Söder O, Svechnikov K: Insulin-Like Peptide 5 Interacts with Sex Hormones and Metabolic Parameters in a Gender and Adiposity Dependent Manner in Humans. Horm Metab Res 48:589-594 (2016)

 

Leipert J, Kässner F, Schuster S, Händel N, Körner A, Kiess W, Garten A: Resveratrol Potentiates Growth Inhibitory Effects of Rapamycin in PTEN-deficient Lipoma Cells by Suppressing p70S6 Kinase Activity. Nutr Cancer 68:342-349 (2016)

 

 

 

2015

 

Landgraf K, Rockstroh D, Wagner IV, Weise S, Tauscher R, Schwartze JT, Löffler D, Bühligen U, Wojan M, Till H, Kratzsch J, Kiess W, Blüher M, Körner A: Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children. Diabetes 64:1249-1261 (2015)

 

Schunter JA, Löffler D, Wiesner T, Kovacs P, Badenhoop K, Aust G, Tönjes A, Müller P, Baber R, Simon JC, Führer D, Pfäffle RW, Thiery J, Stumvoll M, Kiess W, Kratzsch J, Körner A: A novel FoxD3 Variant Is Associated With Vitiligo and Elevated Thyroid Auto-Antibodies. J Clin Endocrinol Metab 100:E1335-1342 (2015)

 

Löffler D, Müller U, Scheuermann K, Friebe D, Gesing J, Bielitz J, Erbs S, Landgraf K, Wagner IV, Kiess W, Körner A: Serum irisin levels are regulated by acute strenuous exercise. J Clin Endocrinol Metab 100:1289-1299 (2015)

 

Rockstroh D, Landgraf K, Wagner IV, Gesing J, Tauscher R, Lakowa N, Kiess W, Bühligen U, Wojan M, Till H, Blüher M, Körner A: Direct evidence of brown adipocytes in different fat depots in children. PLoS One 10:e0117841 (2015)

 

Breitling C, Gross A, Büttner P, Weise S, Schleinitz D, Kiess W, Scholz M, Kovacs P, Körner A: Genetic Contribution of Variants near SORT1 and APOE on LDL Cholesterol Independent of Obesity in Children. PLoS One 10:e0138064 (2015)

 

Qi Q, Downer MK, [8authors], Körner A, [8authors], Scheuermann K, [19authors], Loos RJ, Hu FB, Qi L: Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents. Diabetes 64:2467-2476 (2015)

 

van der Valk RJ, Kreiner-Moller E, [8authors], Körner A, [43authors], Kiess W, Mahajan A, [44authors], Sergeyev E, [15authors], Jaddoe VW, Early Growth Genetics C: A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum.Mol.Genet. 24:1155-1168 (2015)

 

Wilhelm F, Käßner F, Schmid G, Kratzsch J, Laner A, Wabitsch M, Körner A, Kiess W, Garten A: Phosphatidylinositol 3-kinase (PI3K) signalling regulates insulin-like-growth factor binding protein-2 (IGFBP-2) production in human adipocytes. Growth Horm IGF Res 25:115-120 (2015)

 

Quante M, Bruckmann S, Wallborn T, Wolf N, Sergeyev E, Adler M, Hesse M, Geserick M, Naumann S, Koch C, Nivarthi H, Engel C, Körner A, Kiess W, Hiemisch A: Managing incidental findings and disclosure of results in a paediatric research cohort - the LIFE Child Study cohort. J Pediatr Endocrinol Metab 28:75-82 (2015)

 

Kiess W, Wagner IV, Kratzsch J, Körner A: Male Obesity. Endocrinol Metab Clin North Am 44:761-772 (2015)

 

Kiess W, Penke M, Sergeyev E, Neef M, Adler M, Gausche R, Körner A: Childhood obesity at the crossroads. J Pediatr Endocrinol Metab 28:481-484 (2015)

 

Kiess W, Penke M, Gesing J, Hoppmann J, Müller E, Körner A, Kratzsch J, Pfäffle R: Thyroid disorders revisited. J Pediatr Endocrinol Metab 28:731-733 (2015)

 

 

 

2014

 

Mangner N, Scheuermann K, Winzer E, Wagner I, Hoellriegel R, Sandri M, Zimmer M, Mende M, Linke A, Kiess W, Schuler G, Körner A, Erbs S: Childhood obesity: impact on cardiac geometry and function. JACC Cardiovasc Imaging 7:1198-1205 (2014)

 

Bidlingmaier M, Friedrich N, Emeny RT, Spranger J, Wolthers OD, Roswall J, Körner A, Obermayer-Pietsch B, Hubener C, Dahlgren J, Frystyk J, Pfeiffer AF, Doering A, Bielohuby M, Wallaschofski H, Arafat AM: Reference intervals for insulin-like growth factor-1 (igf-i) from birth to senescence: results from a multicenter study using a new automated chemiluminescence IGF-I immunoassay conforming to recent international recommendations. J Clin Endocrinol Metab. 99:1712-1721 (2014)

 

Cousminer DL, Stergiakouli E, Berry DJ, Ang W, Groen-Blokhuis MM, Körner A, [17authors], Neef M, Weise S, [9authors], Kiess W, [6authors], McCarthy MI, Widen E: Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Hum.Mol.Genet. 23:4452-4464 (2014)

 

Wagner IV, Paetzold C, Gausche R, Vogel M, Koerner A, Thiery J, Arsene CG, Henrion A, Guettler B, Keller E, Kiess W, Pfaeffle R, Kratzsch J: Clinical evidence-based cutoff limits for GH stimulation tests in children with a backup of results with reference to mass spectrometry. Eur J Endocrinol 171:389-397 (2014)

 

Schmid GL, Kässner F, Uhlig HH, Körner A, Kratzsch J, Händel N, Zepp FP, Kowalzik F, Laner A, Starke S, Wilhelm FK, Schuster S, Viehweger A, Hirsch W, Kiess W, Garten A: Sirolimus treatment of severe PTEN hamartoma tumor syndrome: case report and in vitro studies. Pediatr Res 75:527-534 (2014)

 

Taubner K, Schubert G, Pulzer F, Pfäffle R, Körner A, Dietz A, Thiery J, Kiess W, Kratzsch J: Serum concentrations of anti-thyroid peroxidase and anti-thyroglobulin antibodies in children and adolescents without apparent thyroid disorders. Clin Biochem 47:3-7 (2014)

 

Kiess W, Kratzsch J, Sergeyev E, Neef M, Adler M, Pfäffle R, Hiemisch A, Körner A: Metabolic syndrome in childhood and adolescence. Clin Biochem 47:695 (2014)

 

 

2013

 

Bernhard F, Landgraf K, Klöting N, Berthold A, Büttner P, Friebe D, Kiess W, Kovacs P, Blüher M, Körner A: Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology. Diabetologia 56:311-322 (2013)

 

Körner A, Wiegand S, Hungele A, Tuschy S, Otto KP, l'Allemand-Jander D, Widhalm K, Kiess W, Holl RW, initiative APV, German Competence Net O: Longitudinal multicenter analysis on the course of glucose metabolism in obese children. Int J Obes (Lond). 37:931-936 (2013)

 

Horikoshi M, Yaghootkar H, Mook-Kanamori DO, [70authors], Kiess W, [17authors], Tönjes A, [11authors], Stumvoll M, [14authors], Körner A, [28authors], Prokopenko I, Freathy RM: New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet. 45:76-82 (2013)

 

Breitfeld J, Heiker JT, Böttcher Y, Schleinitz D, Tönjes A, Weidle K, Krause K, Kuettner EB, Scholz M, Kiess W, Sträter N, Beck-Sickinger AG, Stumvoll M, Körner A, Blüher M, Kovacs P: Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels. J Mol Med (Berl). 91:1285-1292 (2013)

 

Spinnler R, Gorski T, Stolz K, Schuster S, Garten A, Beck-Sickinger AG, Engelse MA, de Koning EJ, Körner A, Kiess W, Maedler K: The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion. PLoS One 8:e54106 (2013)

 

Holstein JD, Patzer O, Körner A, Stumvoll M, Kovacs P, Holstein A: Genetic variants in GCKR, GIPR, ADCY5 and VPS13C and the risk of severe sulfonylurea-induced hypoglycaemia in patients with type 2 diabetes. Exp Clin Endocrinol Diabetes 121:54-57 (2013)

 

Neef M, Weise S, Adler M, Sergeyev E, Dittrich K, Körner A, Kiess W: Health impact in children and adolescents. Best Pract Res Clin Endocrinol Metab 27:229-238 (2013)

 

Rascher W, Kiess W, Körner A: [High blood pressure in obese children and adolescents]. BUNDESGESUNDHEITSBLA 56:492-499 (2013)

 

Sergeyev E, Wagner I, Neef M, Adler M, Körner A, Kiess W: [Carbohydrate metabolism disorders among obese children and adolescents. Diabetes mellitus type 2]. BUNDESGESUNDHEITSBLA 56:511-516 (2013)

 

Wagner IV, Sergeyev E, Dittrich K, Gesing J, Neef M, Adler M, Geserick M, Pfäffle RW, Körner A, Kiess W: [Does childhood obesity affect sexual development?]. BUNDESGESUNDHEITSBLA 56:504-510 (2013)

 

 

2012

 

Landgraf K, Friebe D, Ullrich T, Kratzsch J, Dittrich K, Herberth G, Adams V, Kiess W, Erbs S, Körner A: Chemerin as a Mediator between Obesity and Vascular Inflammation in Children. J Clin Endocrinol Metab. 97:E556-E564 (2012)

 

Melchior C, Schulz A, Windholz J, Kiess W, Schöneberg T, Körner A: Clinical and functional relevance of melanocortin-4 receptor variants in obese german children. Horm Res Paediatr. 78:237-246 (2012)

 

Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, Takeuchi M, Ozawa K, Tauber M, Maffeis C, Morandi A, Buzzetti R, Elliott P, Pouta A, Jarvelin MR, Körner A, Kiess W, Pigeyre M, Caiazzo R, Van Hul W, Van Gaal L, Horber F, Balkau B, Levy-Marchal C, Rouskas K, Kouvatsi A, Hebebrand J, Hinney A, Scherag A, Pattou F, Meyre D, Koshimizu TA, Wolowczuk I, Tsujimoto G, Froguel P: Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature. 19;483:350-354 (2012)

 

Scott RA, Lagou V, Welch RP, Wheeler E, [98authors], Kiess W, [14authors], Kovacs P, [18authors], Stumvoll M, [29authors], Toenjes A, Peyser PA, Beilby JP, Körner A, [40authors], Ingelsson E, Prokopenko I, Barroso I: Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet. 44:991-1005 (2012)

 

Köhler B, Kleinemeier E, Lux A, Hiort O, Grüters A, Thyen U: Satisfaction with Genital Surgery and Sexual Life of Adults with XY Disorders of Sex Development: Results from the German Clinical Evaluation Study. J Clin Endocrinol Metab. 97:577-588 (2012)

 

Quante M, Hesse M, Döhnert M, Fuchs M, Hirsch C, Sergeyev E, Casprzig N, Geserick M, Naumann S, Koch C, Sabin MA, Hiemisch A, Körner A, Kiess W: The LIFE child study: a life course approach to disease and health. BMC Public Health 12:1021 (2012)

 

Raschpichler MC, Sorge I, Hirsch W, Mende M, Sergejev E, Kruber D, Körner A, Schick F: Evaluating childhood obesity: Magnetic-resonance-based quantification of abdominal adipose tissue and liver fat in childen. ROFO-Fortschr Rontg 184:1-9 (2012)

 

Flemming GM, Petzold S, Meigen C, Körner A, Kiess W, Kratzsch J: Is circulating osteocalcin related to adipokines and overweight/obesity in children and adolescents? Exp Clin Endocrinol Diabetes 120:383-387 (2012)

 

Böttcher Y, Körner A, Kovacs P, Kiess W: Obesity genes: Implication in childhood obesity. J Paediatr Child Health 22:31-36 (2012)

 

Wagner IV, Sabin MA, Pfäffle RW, Hiemisch A, Sergeyev E, Körner A, Kiess W: Effects of obesity on human sexual development. Nat Rev Endocrinol 8:246-254 (2012)

 

 

2011

 

Friebe D, Neef M, Kratzsch J, Erbs S, Dittrich K, Garten A, Petzold-Quinque S, Blüher S, Reinehr T, Stumvoll M, Blüher M, Kiess W, Körner A: Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre-B cell colony (PBEF)/visfatin linking obesity and inflammation in humans. Diabetologia 54:1200-1211 (2011)

 

Körner A, Neef M, Friebe D, Erbs S, Kratzsch J, Dittrich K, Blüher S, Kapellen TM, Kovacs P, Stumvoll M, Blüher M, Kiess W: Vaspin is related to gender, puberty and deteriorating insulin sensitivity in children. Int J Obes (Lond). 35:578-586 (2011)

 

Friebe D, Löffler D, Schönberg M, Bernhard F, Büttner P, Landgraf K, Kiess W, Körner A: Impact of metabolic regulators on the expression of the obesity associated genes FTO and NAMPT in human preadipocytes and adipocytes. PLoS One 6:e19526 (2011)

 

Windholz J, Kovacs P, Tönjes A, Dittrich K, Blüher S, Kiess W, Stumvoll M, Körner A: Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children. PLoS One 6:e22101 (2011)

 

Friebe D, Neef M, Erbs S, Dittrich K, Kratzsch J, Kovacs P, Blüher M, Kiess W, Körner A: Retinol binding protein 4 (RBP4) is primarily associated with adipose tissue mass in children. Int J Pediatr Obes. 6:e345-e352 (2011)

 

Friebe D, Kovacs P, Neef M, Blüher S, Schleinitz D, Kiess W, Körner A: The promoter variant -803 G>A in the RBP4 gene is not associated with BMI, metabolic parameters or blood pressure in Caucasian children. Exp Clin Endocrinol Diabetes 119:628-632 (2011)

 

Martos-Moreno GA, Kratzsch J, Körner A, Barrios V, Hawkins F, Kiess W, Argente J: Serum visfatin and vaspin levels in prepubertal children: effect of obesity and weight loss after behavior modifications on their secretion and relationship with glucose metabolism. Int J Obes (Lond). 35:1355-1362 (2011)

 

Müller A, Scholz M, Blankenstein O, Binder G, Pfäffle R, Körner A, Kiess W, Heider A, Bidlingmaier M, Thiery J, Kratzsch J: Harmonization of growth hormone measurements with different immunoassays by data adjustment. Clin Chem Lab Med 49:1135-1142 (2011)

 

Schleinitz D, Klöting N, Böttcher Y, Wolf S, Dietrich K, Tönjes A, Breitfeld J, Enigk B, Halbritter J, Körner A, Schön MR, Jenkner J, Tseng YH, Lohmann T, Dressler M, Stumvoll M, Blüher M, Kovacs P: Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity. PLoS One 6:e16155 (2011)

 

Wiegand S, Thamm M, Kiess W, Körner A, Reinehr T, Krude H, Hoffmeister U, Holl RW: Gamma-glutamyl transferase is strongly associated with degree of overweight and sex. J Pediatr Gastroenterol.Nutr. 52:635-638 (2011)

 

Brandhorst G, Streit F, Kratzsch J, Schiettecatte J, Roth HJ, Luppa PB, Körner A, Kiess W, Binder L, Oellerich M, von Ahsen N: Multicenter evaluation of a new automated electrochemiluminescence immunoassay for the quantification of testosterone compared to liquid chromatography tandem mass spectrometry. Clin Biochem 44:264-267 (2011)

 

Holstein A, Hahn M, Körner A, Stumvoll M, Kovacs P: TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes. BMC Med Genet 12:30.:30 (2011)

 

Schonhoff P, Körner A, Kratzsch J, Pfäffle R, Kiess W: Long term clinical management of girls with Turner syndrome at a center of pediatric endocrinology. Exp Clin Endocrinol Diabetes 119:327-333 (2011)

 

Kiess W, Sergejev E, Körner A, Hebebrand J: [Is it possible to treat obesity in children and adolescents?]. BUNDESGESUNDHEITSBLA 54:527-532 (2011)

 

Blüher S, Sergeyev E, Moser A, Neef M, Hiemisch A, Körner A, Kiess W: Syndromale Adipositas [Syndromal Obesity]. Adipositas 5:(2011)

 

Garten A, Petzold S, Schuster S, Körner A, Kratzsch J, Kiess W: Nampt and its potential role in inflammation and type 2 diabetes. Handb.Exp.Pharmacol. 147-164 (2011)

 

 

2010

 

Ma L, Hanson RL, Traurig MT, Müller YL, Kaur BP, Perez JM, Meyre D, Fu M, Körner A, Franks PW, Kiess W, Kobes S, Knowler WC, Kovacs P, Froguel P, Shuldiner AR, Bogardus C, Baier LJ: Evaluation of A2BP1 as an obesity gene. Diabetes 59:2837-2845 (2010)

 

Kruis T, Klammt J, Galli-Tsinopoulou A, Wallborn T, Schlicke M, Müller E, Kratzsch J, Körner A, Kiess W, Pfäffle R: Heterozygous mutation within a kinase-conserved motif of the insulin-like growth factor I receptor causes intrauterine and postnatal growth retardation. J Clin Endocrinol Metab. 95:1137-1142 (2010)

 

Scherag A, Dina C, Hinney A, Vatin V, Scherag S, Vogel CI, Müller TD, Grallert H, Wichmann HE, Balkau B, Heude B, Jarvelin MR, Hartikainen AL, Levy-Marchal C, Weill J, Delplanque J, Körner A, Kiess W, Kovacs P, Rayner NW, Prokopenko I, McCarthy MI, Schafer H, Jarick I, Boeing H, Fisher E, Reinehr T, Heinrich J, Rzehak P, Berdel D, Borte M, Biebermann H, Krude H, Rosskopf D, Rimmbach C, Rief W, Fromme T, Klingenspor M, Schurmann A, Schulz N, Nothen MM, Muhleisen TW, Erbel R, Jockel KH, Moebus S, Boes T, Illig T, Froguel P, Hebebrand J, Meyre D: Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. PLoS Genet 6:e1000916 (2010)

 

Schleinitz D, Klöting N, Körner A, Berndt J, Reichenbacher M, Tönjes A, Ruschke K, Böttcher Y, Dietrich K, Enigk B, Filz M, Schön MR, Jenkner J, Kiess W, Stumvoll M, Blüher M, Kovacs P: Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression. Obesity (Silver.Spring). 18:1218-1225 (2010)

 

Rudolph H, Blüher S, Falkenberg C, Neef M, Körner A, Wurz J, Kiess W, Brähler E: Perception of body weight status: a case control study of obese and lean children and adolescents and their parents. Obes Facts. 3:83-91 (2010)

 

Garten A, Petzold S, Barnikol-Oettler A, Körner A, Thasler WE, Kratzsch J, Kiess W, Gebhardt R: Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes. Biochem Biophys Res Commun 391:376-381 (2010)

 

Wagner IV, Ketzscher R, Dittrich K, Neef M, Kiess W, Körner A: The impact of blood pressure measurement in children and adolescents with obesity – diagnostic pitfalls. Adipositas 4:197-201 (2010)

 

Ceglarek U, Werner M, Kortz L, Körner A, Kiess W, Thiery J, Kratzsch J: Preclinical challenges in steroid analysis of human samples. J Steroid Biochem Mol Biol. 121:505-512 (2010)

 

 

2009

 

Meyre D, Delplanque J, Chevre JC, Lecoeur C, Lobbens S, Gallina S, Durand E, Vatin V, Degraeve F, Proenca C, Gaget S, Körner A, Kovacs P, Kiess W, Tichet J, Marre M, Hartikainen AL, Horber F, Potoczna N, Hercberg S, Levy-Marchal C, Pattou F, Heude B, Tauber M, McCarthy MI, Blakemore AI, Montpetit A, Polychronakos C, Weill J, Coin LJ, Asher J, Elliott P, Jarvelin MR, Visvikis-Siest S, Balkau B, Sladek R, Balding D, Walley A, Dina C, Froguel P: Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet. 41:157-159 (2009)

 

Walther C, Gaede L, Adams V, Gelbrich G, Leichtle A, Erbs S, Sonnabend M, Fikenzer K, Körner A, Kiess W, Bruegel M, Thiery J, Schuler G: Effect of increased exercise in school children on physical fitness and endothelial progenitor cells: a prospective randomized trial. Circulation 120:2251-2259 (2009)

 

Böttcher Y, Unbehauen H, Klöting N, Ruschke K, Körner A, Schleinitz D, Tönjes A, Enigk B, Wolf S, Dietrich K, Koriath M, Scholz GH, Tseng YH, Dietrich A, Schön MR, Kiess W, Stumvoll M, Blüher M, Kovacs P: Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity. Diabetes 58:2119-2128 (2009)

 

Völkl TM, Simm D, Körner A, Rascher W, Kiess W, Kratzsch J, Dörr HG: Does an altered leptin axis play a role in obesity among children and adolescents with classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency? Eur J Endocrinol 160:239-247 (2009)

 

Völkl TM, Simm D, Körner A, Kiess W, Kratzsch J, Dörr HG: Adiponectin levels are high in children with classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. Acta Paediatr. 98:885-891 (2009)

 

Kiess W, Blüher S, Kapellen T, Körner A: Metabolic syndrome in children and adolescents: prevalence, public health issue, and time for initiative. J Pediatr.Gastroenterol.Nutr. 49:268-271 (2009)

 

Garten A, Petzold S, Körner A, Imai S, Kiess W: Nampt: linking NAD biology, metabolism and cancer. Trends Endocrinol Metab. 20:130-138 (2009)

 

Beige J, Heipmann K, Stumvoll M, Körner A, Kratzsch J: Paradoxical role for adiponectin in chronic renal diseases? An example of reverse epidemiology. Expert Opin Pharmacother 13:163-173 (2009)

 

Blüher S, Hauskeller F, Kapellen TM, Körner A, Neef M, Jennewein R, Zschaler S, Gausche R, Meigen C, Burgold A, Pfäffle R, Kiess W: Aktuelle Präventionsansätze gegen Adipositas und Typ 2 Diabetes bei Kindern und Jugendlichen. (2009)

 

Melchior C, Kiess W, Dittrich K, Schulz A, Schöneberg T, Körner A: [Slim despite a genetic predisposition for obesity--influence of environmental factors as chance? A case report]. Deut Med Wochenschr 134:1047-1050 (2009)

 

 

2008

 

Benzinou M, Creemers JW, Choquet H, Lobbens S, Dina C, Durand E, Guerardel A, Boutin P, Jouret B, Heude B, Balkau B, Tichet J, Marre M, Potoczna N, Horber F, Le Stunff C, Czernichow S, Sandbaek A, Lauritzen T, Borch-Johnsen K, Andersen G, Kiess W, Körner A, Kovacs P, Jacobson P, Carlsson LM, Walley AJ, Jorgensen T, Hansen T, Pedersen O, Meyre D, Froguel P: Common nonsynonymous variants in PCSK1 confer risk of obesity. Nat Genet. 40:943-945 (2008)

 

Kovacs P, Berndt J, Ruschke K, Klöting N, Schön MR, Körner A, Stumvoll M, Blüher M: TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus. Metabolism. 57:1227-1231 (2008)

 

Kratzsch J, Schubert G, Pulzer F, Pfäffle R, Körner A, Dietz A, Rauh M, Kiess W, Thiery J: Reference intervals for TSH and thyroid hormones are mainly affected by age, body mass index and number of blood leucocytes, but hardly by gender and thyroid autoantibodies during the first decades of life. Clin Biochem 41:1091-1098 (2008)

 

Till HK, Muensterer O, Keller A, Körner A, Blueher S, Merkle R, Kiess W: Laparoscopic sleeve gastrectomy achieves substantial weight loss in an adolescent girl with morbid obesity. Eur J Pediatr Surg 18:47-49 (2008)

 

Heger S, Körner A, Meigen C, Gausche R, Keller A, Keller E, Kiess W: Impact of weight status on the onset and parameters of puberty: analysis of three representative cohorts from central Europe. J Pediatr Endocrinol Metab. 21:865-877 (2008)

 

Walther C, Adams V, Bothur I, Drechsler K, Fikenzer S, Sonnabend M, Bublitz B, Körner A, Erbs S, Busse M, Schuler G: Increasing physical education in high school students: effects on concentration of circulating endothelial progenitor cells. Eur J Cardiovasc Prev Rehabil 15:416-422 (2008)

 

Körner A, Kratzsch J, Gausche R, Blüher S, Kapellen T, Pulzer F, Behrens M, Kiess W: Metabolic syndrome in children and adolescents--risk for sleep-disordered breathing and obstructive sleep-apnoea syndrome? Arch Physiol Biochem 114:237-243 (2008)

 

Körner A, Kiess W, Stumvoll M, Kovacs P: Polygenic contribution to obesity: genome-wide strategies reveal new targets. Front Horm.Res. 36:12-36 (2008)

 

Kiess W, Petzold S, Töpfer M, Garten A, Blüher S, Kapellen T, Körner A, Kratzsch J: Adipocytes and adipose tissue. Best Pract Res Clin Endocrinol Metab 22:135-153 (2008)

Rohde C, Kapellen S, Schmidt K, Körner A, Till H, Sachse U, Kiess W: Choice of food for children and teenagers in a hospital setting: How effective are interventions? [Nahrungsangebote im Krankenhaus und Auswahlverhalten bei Kindern und Jugendlichen: Was ko¨nnen Interventionen Bewirken?]. Ernährungs Umschau 55:144-150 (2008)

 

 

 

2007

 

Revollo JR, Körner A, Mills KF, Satoh A, Wang T, Garten A, Dasgupta B, Sasaki Y, Wolberger C, Townsend RR, Milbrandt J, Kiess W, Imai S: Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. Cell Metab 6:363-375 (2007)

 

Körner A, Böttcher Y, Enigk B, Kiess W, Stumvoll M, Kovacs P: Effects of genetic variation in the visfatin gene (PBEF1) on obesity, glucose metabolism, and blood pressure in children. Metabolism. 56:772-777 (2007)

 

Körner A, Pazaitou-Panayiotou K, Kelesidis T, Kelesidis I, Williams CJ, Kaprara A, Bullen J, Neuwirth A, Tseleni S, Mitsiades N, Kiess W, Mantzoros CS: Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies. J Clin Endocrinol Metab. 92:1041-1048 (2007)

 

Körner A, Garten A, Blüher M, Tauscher R, Kratzsch J, Kiess W: Molecular characteristics of serum visfatin and differential detection by immunoassays. J Clin Endocrinol Metab. 92:4783-4791 (2007)

 

Körner A, Berndt J, Stumvoll M, Kiess W, Kovacs P: TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children. J Clin Endocrinol Metab. 92:1956-1960 (2007)

 

Körner A, Ma L, Franks PW, Kiess W, Baier LJ, Stumvoll M, Kovacs P: Sex-specific effect of the Val1483Ile polymorphism in the fatty acid synthase gene (FAS) on body mass index and lipid profile in Caucasian children. Int J Obes (Lond). 31:353-358 (2007)

 

Körner A, Gelbrich G, Müller G, Reich A, Deutscher K, Godicke R, Gronemann B, Kiess W: Critical evaluation of methods for determination of body fat content in children: back to basic parameters? Horm Metab Res. 39:31-40 (2007)

 

Dina C, Meyre D, Gallina S, Durand E, Körner A, Jacobson P, Carlsson LM, Kiess W, Vatin V, Lecoeur C, Delplanque J, Vaillant E, Pattou F, Ruiz J, Weill J, Levy-Marchal C, Horber F, Potoczna N, Hercberg S, Le Stunff C, Bougneres P, Kovacs P, Marre M, Balkau B, Cauchi S, Chevre JC, Froguel P: Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet. 39:724-726 (2007)

 

Berndt J, Kovacs P, Ruschke K, Klöting N, Fasshauer M, Schön MR, Körner A, Stumvoll M, Blüher M: Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes. Diabetologia 50:1472-1480 (2007)

 

Bohlen F, Kratzsch J, Mueller M, Seidel B, Friedman-Einat M, Witzigmann H, Teupser D, Körner A, Storck M, Thiery J: Leptin inhibits cell growth of human vascular smooth muscle cells. Vascul Pharmacol 46:67-71 (2007)

 

Körner A, Kratzsch J, Gausche R, Schaab M, Erbs S, Kiess W: New predictors of the metabolic syndrome in children--role of adipocytokines. Pediatr Res 61:640-645 (2007)

 

 

2006

 

Böttcher Y, Körner A, Reinehr T, Enigk B, Kiess W, Stumvoll M, Kovacs P: ENPP1 variants and haplotypes predispose to early onset obesity and impaired glucose and insulin metabolism in German obese children. J Clin Endocrinol Metab. 91:4948-4952 (2006)

 

Kratzsch J, Knerr I, Galler A, Kapellen T, Raile K, Körner A, Thiery J, Dötsch J, Kiess W: Metabolic decompensation in children with type 1 diabetes mellitus associated with increased serum levels of the soluble leptin receptor. Eur J Endocrinol 155:609-614 (2006)

 

Kiess W, Blüher S, Kapellen T, Garten A, Klammt J, Kratzsch J, Körner A: Physiology of obesity in childhood and adolescence. Curr Pediatr 16:123-131 (2006)

 

 

2005

 

Körner A, Wabitsch M, Seidel B, Fischer-Posovszky P, Berthold A, Stumvoll M, Blüher M, Kratzsch J, Kiess W: Adiponectin expression in humans is dependent on differentiation of adipocytes and down-regulated by humoral serum components of high molecular weight. Biochem Biophys Res Commun 337:540-550 (2005)

 

Kratzsch J, Schubring C, Stitzel B, Böttner A, Berthold A, Thiery J, Kiess W: Inverse changes in the serum levels of the soluble leptin receptor and leptin in neonates: relations to anthropometric data. J Clin.Endocrinol.Metab. 90:2212-2217 (2005)

 

Gerber M, Böttner A, Seidel B, Lammert A, Bär J, Schuster E, Thiery J, Kiess W, Kratzsch J: Serum resistin levels of obese and lean children and adolescents: biochemical analysis and clinical relevance. J Clin Endocrinol Metab 90:4503-4509 (2005)

 

Sorensen DB, Johnsen PF, Bibby BM, Böttner A, Bornstein SR, Eisenhofer G, Pacak K, Hansen AK: PNMT Transgenic Mice Have an Aggressive Phenotype. Horm Metab Res. 37:159-163 (2005)

 

Körner A, Kratzsch J, Kiess W: Adipocytokines: leptin-the classical, resistin-the controversial, adiponectin-the promising, and more to come. Best Pract Res Clin Endocrinol Metab 19:525-546 (2005)

 

Böttner A, Kratzsch J, Liebermann S, Keller A, Pfäffle RW, Kiess W, Keller E: Comparison of adrenal function tests in children--the glucagon stimulation test allows the simultaneous assessment of adrenal function and growth hormone response in children. J Pediatr Endocrinol Metab. 18:433-442 (2005)

 

Körner A, Blüher S, Kapellen T, Garten A, Klammt J, Kratzsch J, Kiess W: Obesity in childhood and adolescence: a review in the interface between adipocyte physiology and clinical challenges. Hormones.(Athens.). 4:189-199 (2005)

 

 

2004

 

Böttner A, Kratzsch J, Müller G, Kapellen TM, Blüher S, Keller E, Blüher M, Kiess W: Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels. J Clin Endocrinol Metab 89:4053-4061 (2004)

 

Böttner A, Keller E, Kratzsch J, Stobbe H, Weigel JF, Keller A, Hirsch W, Kiess W, Blum WF, Pfaffle RW: PROP1 Mutations Cause Progressive Deterioration of Anterior Pituitary Function including Adrenal Insufficiency: A Longitudinal Analysis. J Clin Endocrinol Metab 89:5256-5265 (2004)

 

Reinehr T, Wabitsch M, Andler W, Beyer P, Böttner A, Chen-Stute A, Fromme C, Hampel O, Keller KM, Kilian U, Kolbe H, Lob-Corzilius T, Marg W, Mayer H, Mohnike K, Oepen J, Povel C, Richter B, Riedinger N, Schauerte G, Schmahlfeldt G, Siegfried W, Smuda P, Stachow R, Egmond-Frohlich A, Weiten J, Wiegand S, Witte S, Zindel V, Holl RW: Medical care of obese children and adolescents. APV: a standardised multicentre documentation derived to study initial presentation and cardiovascular risk factors in patients transferred to specialised treatment institutions. Eur J Pediatr 163:308-312 (2004)

 

Kiess W, Böttner A, Blüher S, Raile K, Galler A, Kapellen TM: Type 2 diabetes mellitus in children and adolescents--the beginning of a renal catastrophe? Nephrol Dial Transplant 19:2693-2696 (2004)

 

Kapellen TM, Böttner A, Galler A, Raile K, Nietzschmann U, Kiess W: Treatment of adolescents with type 2 diabetes. Klin Pädiatr 216:57-61 (2004)

 

Kapellen TM, Galler A, Böttner A, Kiess W: Epidemiology, treatment and prevention of type 2 diabetes in children and adolescents. Deut Med Wochenschr 129:1519-1523 (2004)

 

Kiess W, Blüher S, Kapellen T, Böttner A: Obesity, childhood and adolescence. 3:403-407 (2004)

 

 

2003

 

Zastrow O, Seidel B, Kiess W, Thiery J, Keller E, Böttner A, Kratzsch J: The soluble leptin receptor is crucial for leptin action: evidence from clinical and experimental data. Int J Obes (Lond). 27:1472-1478 (2003)

 

Kiess W, Böttner A, Blüher S, Raile K, Seidel B, Kapellen T, Keller E, Kratzsch J: Pharmacoeconomics of obesity management in childhood and adolescence. Expert Opin Pharmacother 4:1471-1477 (2003)

 

Kiess W, Böttner A, Raile K, Kapellen T, Müller G, Galler A, Paschke R, Wabitsch M: Type 2 Diabetes mellitus in Children and Adolescents: A Review from a European Perspective. Horm Res Paediatr. 59:77-84 (2003)

 

 

2002

 

Böttner A, Daneschnejad S, Handrick W, Schuster V, Liebert UG, Kiess W: A season of aseptic meningitis in Germany: epidemiologic, clinical and diagnostic aspects. Pediatr Infect Dis J 21:1126-1132 (2002)

 

Kratzsch J, Lammert A, Böttner A, Seidel B, Müller G, Thiery J, Hebebrand J, Kiess W: Circulating soluble leptin receptor and free leptin index during childhood, puberty, and adolescence. J Clin Endocrinol Metab. 87:4587-4594 (2002)

 

Galon J, Franchimont D, Hiroi N, Frey G, Böttner A, Ehrhart-Bornstein M, O'Shea JJ, Chrousos GP, Bornstein SR: Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells. FASEB J 16:61-71 (2002)

 

Lammert A, Brockmann G, Renne U, Kiess W, Böttner A, Thiery J, Kratzsch J: Different isoforms of the soluble leptin receptor in non-pregnant and pregnant mice. Biochem Biophys Res Commun 298:798-804 (2002)

 

Kasperlik-Zaluska AA, Roslonowska E, Bornstein SR, Pacak K, Böttner A, Eisenhofer G: Utility of plasma metanephrines in the diagnosis of adrenal incidentalomas. Pol J Endocrinol 53:549-556 (2002) 

 

Kiess W, Böttner A: Obesity in the adolescent. Adolesc.Med. 13:181-190 (2002)

 

 

2001

 

Glasow A, Kiess W, Anderegg U, Berthold A, Böttner A, Kratzsch J: Expression of leptin (Ob) and leptin receptor (Ob-R) in human fibroblasts: regulation of leptin secretion by insulin. J Clin.Endocrinol.Metab. 86:4472-4479 (2001)

 

Lammert A, Kiess W, Böttner A, Glasow A, Kratzsch J: Soluble leptin receptor represents the main leptin binding activity in human blood. Biochem Biophys Res Commun 283:982-988 (2001)

 

Böttner A, Bornstein SR: Lessons learned from gene targeting and transgenesis for adrenal physiology and disease. Rev Endocr MetabDisord 2:275-287 (2001)

 

Kiess W, Reich A, Müller G, Galler A, Kapellen T, Raile K, Böttner A, Seidel B, Kratzsch J: Obesity in childhood and adolescence: clinical diagnosis and management. J Pediatr Endocrinol Metab 14 Suppl 6:1431-40.:1431-1440 (2001)

 

 

2000

 

Böttner A, Eisenhofer G, Friberg P, Rundqvist B, Bornstein SR: Serum leptin levels in heart failure patients may be altered differently according to clinical stage. Eur Heart J 21:334-335 (2000)

 

Böttner A, Haidan A, Eisenhofer G, Kristensen K, Castle AL, Scherbaum WA, Schneider H, Chrousos GP, Bornstein SR: Increased body fat mass and suppression of circulating leptin levels in response to hypersecretion of epinephrine in phenylethanolamine-N-methyltransferase (PNMT)-overexpressing mice. Endocrinology 141:4239-4246 (2000)

 

Bornstein SR, Tian H, Haidan A, Böttner A, Hiroi N, Eisenhofer G, McCann SM, Chrousos GP, Roffler-Tarlov S: Deletion of tyrosine hydroxylase gene reveals functional interdependence of adrenocortical and chromaffin cell system in vivo. P Natl Acad Sci USA 97:14742-14747 (2000)

 

 

1999

 

Böttner A, Eisenhofer G, Friberg P, Rundqvist B, Bornstein SR: Hyperleptinaemia does not correlate with plasma catecholamine levels in chronic heart failure. Eur Heart J 20:1051-1052 (1999)

 

Böttner A, Eisenhofer G, Torpy DJ, Ehrhart-Bornstein M, Keiser HR, Chrousos GP, Bornstein SR: Lack of leptin suppression in response to hypersecretion of catecholamines in pheochromocytoma patients. Metabolism. 48:543-545 (1999)

 

Bornstein S, Böttner A, Chrousos G: Knocking out the stress response. Mol.Psychiatry 4:403-407 (1999)

 

 

 

1998

 

Breidert M, Böttner A, Möller S, Herberg L, Bornstein S: Apoptosis in the adrenal gland of non-obese diabetic (NOD) mice. Exp Clin Endocrinol Diabetes 106:478-483 (1998)

 

Uhlmann K, Böttner A, Haidan A, Kino T, Wiznerowicz M, Trzeciak H, Ehrhart-Bornstein M, Bornstein SR: Basal catecholamine and cortisol secretion in primary chromaffin cell cultures before and after purification and retroviral transfection. Endocr Res 24:753-757 (1998)

 

 


 
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