Klinik und Poliklinik für Kinder- und Jugendmedizin
 Universitätsmedizin Leipzig

Publications

Overview of selected publications.

List of all publications (PDF 231 kB)

 

Kess A, Spielau U, Beger C, Gausche R, Vogel M, Lipek T, Körner A, Pfaffle R, Kiess W: Further stabilization and even decrease in the prevalence rates of overweight and obesity in German children and adolescents from 2005 to 2015: a cross-sectional and trend analysis. Public health nutrition 1-9 (2017)  PubMed

 

Bussler S, Vogel M, Pietzner D, Harms K, Buzek T, Penke M, Handel N, Körner A, Baumann U, Kiess W, Flemming G: New pediatric percentiles of liver enzyme serum levels (ALT, AST, GGT): Effects of age, sex, BMI and pubertal stage. Hepatology (Baltimore, Md.) (2017) PubMed

 

Wheeler E, Leong A, Liu CT, [80authors], Kiess W, [61authors], Blüher M, [25authors], Körner A, [45authors], Meigs JB: Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS medicine 14:e1002383 (2017) PubMed

 

Bussler S, Penke M, Flemming G, Elhassan YS, Kratzsch J, Sergeyev E, Lipek T, Vogel M, Spielau U, Körner A, de Giorgis T, Kiess W: Novel Insights in the Metabolic Syndrome in Childhood and Adolescence. Hormone research in paediatrics (2017) PubMed

 

Hendricks AE, Bochukova EG, Marenne G, Keogh JM, Atanassova N, Bounds R, Wheeler E, Mistry V, Henning E, Körner A, Muddyman D, McCarthy S, Hinney A, Hebebrand J, Scott RA, Langenberg C, Wareham NJ, Surendran P, Howson JM, Butterworth AS, Danesh J, Nordestgaard BG, Nielsen SF, Afzal S, Papadia S, Ashford S, Garg S, Millhauser GL, Palomino RI, Kwasniewska A, Tachmazidou I, O'Rahilly S, Zeggini E, Barroso I, Farooqi IS: Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity. Scientific reports 7:4394 (2017) PubMed

 

Raulien N, Friedrich K, Strobel S, Rubner S, Baumann S, von Bergen M, Körner A, Krueger M, Rossol M, Wagner U: Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes. Frontiers in immunology 8:609 (2017) PubMed

 

Windholz J, Kovacs P, Schlicke M, Franke C, Mahajan A, Morris AP, Lemke JR, Klammt J, Kiess W, Schoneberg T, Pfaffle R, Korner A: Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children. Journal of pediatric endocrinology & metabolism : JPEM 30:507-515 (2017) PubMed

 

Stanik J, Kratzsch J, Landgraf K, Scheuermann K, Spielau U, Gausche R, Gasperikova D, Kiess W, Körner A: Concordance of bioactive vs. total immunoreactive serum leptin levels in children with severe early onset obesity. PloS one 12:e0178107 (2017) PubMed

 

Junge J, Engel C, Vogel M, Naumann S, Loffler M, Thiery J, Kratzsch J, Kiess W, Körner A: Neck circumference is similarly predicting for impairment of glucose tolerance as classic anthropometric parameters among healthy and obese children and adolescents. Journal of pediatric endocrinology & metabolism : JPEM 30:643-650 (2017) PubMed

 

Kiess W, Penke M, Kratzsch J, Vogel M, Kapellen T, Hoppmann J, Gesing J, Gausche R, Klamt S, Körner A, Pfaffle R: Pediatric endocrinology is pediatrics is public health. Journal of pediatric endocrinology & metabolism : JPEM (2017) PubMed

 

Landgraf K, Schuster S, Meusel A, Garten A, Riemer T, Schleinitz D, Kiess W, Körner A: Short-term overfeeding of zebrafish with normal or high-fat diet as a model for the development of metabolically healthy versus unhealthy obesity. BMC physiology 17:4 (2017) PubMed

 

Löffler D, Behrendt S, Creemers JWM, Klammt J, Aust G, Stanik J, Kiess W, Kovacs P, Körner A: Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism. Molecular metabolism EPub:(2017) PubMed

 

Schreier M, Schwartze JT, Landgraf K, Scheuermann K, Erbs S, Herberth G, Pospisilik JA, Kratzsch J, Kiess W, Körner A: Osteopontin is BMI-independently Related to Early Endothelial Dysfunction in Children. J Clin Endocrinol Metab 101:4161-4169 (2016) PubMed

 

Dalgaard K, Landgraf K, Heyne S, Lempradl A, Longinotto J, Gossens K, Ruf M, Orthofer M, Strogantsev R, Selvaraj M, Lu TT, Casas E, Teperino R, Surani MA, Zvetkova I, Rimmington D, Tung YC, Lam B, Larder R, Yeo GS, O'Rahilly S, Vavouri T, Whitelaw E, Penninger JM, Jenuwein T, Cheung CL, Ferguson-Smith AC, Coll AP, Körner A, Pospisilik JA: Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity. Cell 164:353-364 (2016) IF: 32.24 PubMed

 

Horikoshi M, [55authors], P K, [38authors], A T, M S, [3authors], W K, A K, [59uthors], MI M, Freathy RM: Genome-wide associations for birth weight and correlations with adult disease. Nature 538:248-252 (2016) PubMed

 

Landgraf K, Rockstroh D, Wagner IV, Weise S, Tauscher R, Schwartze JT, Löffler D, Bühligen U, Wojan M, Till H, Kratzsch J, Kiess W, Blüher M, Körner A: Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children. Diabetes 64:1249-1261 (2015) IF 8.10 Citations: 1 PubMed


Bernhard F, Landgraf K, Klöting N, Berthold A, Büttner P, Friebe D, Kiess W, Blüher M, Körner A: Functional relevance of obesity susceptibility genes from GWAs for human adipocyte differentiation. Diabetologia 56:311-322 (2013) IF: 6.814 PubMed


Landgraf K, Friebe D, Ullrich T, Kratzsch J, Dittrich K, Herberth G, Adams V, Kiess W, Erbs S, Körner A: Chemerin as a Mediator between Obesity and Vascular Inflammation in Children. J Clin Endocrinol Metab 97:E556-E564 (2012). IF: 5.967 Citations: 2 PubMed

 

Horikoshi M, Yaghootkar H, Mook-Kanamori DO, [70 authors], Kiess W, [17 authors], Tönjes A, [11 authors], Stumvoll M, [14 authors], Körner A, [28 authors], Prokopenko I, Freathy RM: Novel loci associated with birth weight reveal genetic links between intrauterine growth and adult height and metabolism. Nat genet Epub IF: 35.532 PubMed

 

Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, Takeuchi M, Ozawa K, Tauber M, Maffeis C, Morandi A, Buzzetti R, Elliott P, Pouta A, Jarvelin MR, Körner A, Kiess W, Pigeyre M, Caiazzo R, Van Hul W, Van Gaal L, Horber F, Balkau B, Levy-Marchal C, Rouskas K, Kouvatsi A, Hebebrand J, Hinney A, Scherag A, Pattou F, Meyre D, Koshimizu TA, Wolowczuk I, Tsujimoto G, Froguel P: Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature 19;483:350-354 (2012). IF: 36.280 Citations: 5 PubMed

 

Friebe D, Neef M, Kratzsch J, Erbs S, Dittrich K, Garten A, Petzold-Quinque S, Blüher S, Reinehr T, Stumvoll M, Blüher M, Kiess W, Körner A: Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre-B cell colony (PBEF)/visfatin linking obesity and inflammation in humans. Diabetologia 54:1200-1211 (2011). IF: 6.814 Citations: 14 PubMed

 

Körner A, Neef M, Friebe D, Erbs S, Kratzsch J, Dittrich K, Blüher S, Kapellen TM, Kovacs P, Stumvoll M, Blüher M, Kiess W: Vaspin is related to gender, puberty and deteriorating insulin sensitivity in children. Int J Obes (Lond) 35:578-586 (2011). IF: 4.691 Citations: 4 PubMed

 

Friebe D*, Löffler D*, Schönberg M, Bernhard F, Büttner P, Landgraf K, Kiess W, Körner A: Impact of metabolic regulators on the expression of the obesity associated genes FTO and NAMPT in human preadipocytes and adipocytes. PLoS ONE 6:e19526 (2011). IF: 4.092 Citations: 1 PubMed

 

Windholz J*, Kovacs P*, Tönjes A, Dittrich K, Blüher S, Kiess W, Stumvoll M, Körner A: Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children. PLoS ONE 6:e22101 (2011). IF: 4.092 Citations: 0 PubMed

 

Scherag A, Dina C, Hinney A, Vatin V, Scherag S, Vogel CI, Müller TD, Grallert H, Wichmann HE, Balkau B, Heude B, Jarvelin MR, Hartikainen AL, Levy-Marchal C, Weill J, Delplanque J, Körner A, Kiess W, Kovacs P, Rayner NW, Prokopenko I, McCarthy MI, Schafer H, Jarick I, Boeing H, Fisher E, Reinehr T, Heinrich J, Rzehak P, Berdel D, Borte M, Biebermann H, Krude H, Rosskopf D, Rimmbach C, Rief W, Fromme T, Klingenspor M, Schurmann A, Schulz N, Nothen MM, Muhleisen TW, Erbel R, Jockel KH, Moebus S, Boes T, Illig T, Froguel P, Hebebrand J, Meyre D: Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. PLoS Genet 6:e1000916 (2010). IF: 8.694 Citations: 54 PubMed

 

Meyre D, Delplanque J, Chevre JC, Lecoeur C, Lobbens S, Gallina S, Durand E, Vatin V, Degraeve F, Proenca C, Gaget S, Körner A, Kovacs P, Kiess W, Tichet J, Marre M, Hartikainen AL, Horber F, Potoczna N, Hercberg S, Levy-Marchal C, Pattou F, Heude B, Tauber M, McCarthy MI, Blakemore AI, Montpetit A, Polychronakos C, Weill J, Coin LJ, Asher J, Elliott P, Jarvelin MR, Visvikis-Siest S, Balkau B, Sladek R, Balding D, Walley A, Dina C, Froguel P: Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet 41:157-159 (2009). IF: 35.532 Citations: 196 PubMed

 

Walther C, Gaede L, Adams V, Gelbrich G, Leichtle A, Erbs S, Sonnabend M, Fikenzer K, Körner A, Kiess W, Bruegel M, Thiery J, Schuler G: Effect of increased exercise in school children on physical fitness and endothelial progenitor cells: a prospective randomized trial. Circulation 120:2251-2259 (2009). IF: 14.739 Citations: 18 PubMed

 

Benzinou M, Creemers JW, Choquet H, Lobbens S, Dina C, Durand E, Guerardel A, Boutin P, Jouret B, Heude B, Balkau B, Tichet J, Marre M, Potoczna N, Horber F, Le Stunff C, Czernichow S, Sandbaek A, Lauritzen T, Borch-Johnsen K, Andersen G, Kiess W, Körner A, Kovacs P, Jacobson P, Carlsson LM, Walley AJ, Jorgensen T, Hansen T, Pedersen O, Meyre D, Froguel P: Common nonsynonymous variants in PCSK1 confer risk of obesity. Nat Genet 40:943-945 (2008). IF: 35.532 Citations: 75 PubMed

 

Körner A, Berndt J, Stumvoll M, Kiess W, Kovacs P: TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children. J Clin Endocrinol Metab 92:1956-1960 (2007). IF: 5.967 Citations: 16 PubMed

 

Revollo JR*, Körner A*, Mills KF, Satoh A, Wang T, Garten A, Dasgupta B, Sasaki Y, Wolberger C, Townsend RR, Milbrandt J, Kiess W, Imai S: Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. Cell Metab 6:363-375 (2007). IF: 13.668 Citations: 232 PubMed

 

Körner A, Garten A, Blüher M, Tauscher R, Kratzsch J, Kiess W: Molecular characteristics of serum visfatin and differential detection by immunoassays. J Clin Endocrinol Metab 92:4783-4791 (2007). IF: 5.967 Citations: 62 PubMed

 

Körner A, Kratzsch J, Gausche R, Schaab M, Erbs S, Kiess W: New predictors of the metabolic syndrome in children--role of adipocytokines. Pediatr Res 61:640-645 (2007). IF: 2.7 Citations: 37 PubMed

 

Dina C, Meyre D, Gallina S, Durand E, Körner A, Jacobson P, Carlsson LM, Kiess W, Vatin V, Lecoeur C, Delplanque J, Vaillant E, Pattou F, Ruiz J, Weill J, Levy-Marchal C, Horber F, Potoczna N, Hercberg S, Le Stunff C, Bougneres P, Kovacs P, Marre M, Balkau B, Cauchi S, Chevre JC, Froguel P: Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 39:724-726 (2007). IF: 35.532 Citations: 440 PubMed

 

Körner A, Wabitsch M, Seidel B, Fischer-Posovszky P, Berthold A, Stumvoll M, Blüher M, Kratzsch J, Kiess W: Adiponectin expression in humans is dependent on differentiation of adipocytes and down-regulated by humoral serum components of high molecular weight. Biochem Biophys Res Commun 337:540-550 (2005). IF: 2.484 Citations: 43 PubMed

 

Böttner A, Kratzsch J, Müller G, Kapellen TM, Blüher S, Keller E, Blüher M, Kiess W: Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels. J Clin Endocrinol Metab 89:4053-4061 (2004). IF: 5.967 Citations: 191 PubMed

 

 
Letzte Änderung: 03.09.2018, 12:29 Uhr
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