Klinik und Poliklinik für Kinder- und Jugendmedizin
 Universitätsmedizin Leipzig

Physiology of Lung Epithelia - AG Prof. Thome

Alveolar fluid clearance from the distal airspaces is mainly driven by vectorial sodium transport, where sodium enters the alveolar epithelial cells through apically located sodium channels (ENaC) and is extruded by basolaterally operating Na,K-ATPases. Hence sodium transport plays a crucial role in the immediate postnatal fluid clearance and the reabsorption of pulmonary edema. Our group aims to analyze new strategies to enhance epithelial sodium transport and thereby improve the morbidity and mortality of pulmonary complications associated with a reduced alveolar fluid clearance.

Plus Symbol alveolar sodium and fluid absorption

Link zur Abteilung für Neonatologie

Letzte Änderung: 22.01.2018, 12:06 Uhr
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Klinik und Poliklinik für Kinder- und Jugendmedizin