Klinik und Poliklinik für Kinder- und Jugendmedizin
 Universitätsmedizin Leipzig

Antje Körner Group: "Childhood Obesity & Endocrinology"

Our group is interested in the causes and consequences of childhood obesity. Commonly, (childhood) obesity is supposed to result from an imbalance of energy intake and output. But is it really as simple as that? We are interested in questions like: When does obesity in children develop? What favours development of obesity in children? What happens in the adipose tissue itself? What is the connection between excess adipose tissue and the development of comorbidities in children?
We are addressing such questions in our dedicated team of biologists, nutrional scientists, physician scientists, clinical and technical assistants. We combine methods of basic experimental scienctific research along with clinical and genetic studies in children and adolescents.

See our “research topics” for more information on the projects.

Unsere Arbeitsgruppe beschäftigt sich mit den Ursachen und Folgen von kindlicher Adipositas. Am häufigsten resultiert kindliche Adipositas aus einem Ungleichgewicht von Energieaufnahme und –verbrauch.  Aber ist dies wirklich so einfach zu erklären?
Wir stellen uns aus diesem Grund Forschungsfragen wie: Wann entwickelt sich Adipositas bei Kindern? Was begünstigt die Entwicklung von Adipositas bei Kindern? Was passiert dabei im Fettgewebe selbst? Wie ist der Zusammenhang zwischen übermäßigem Fettgewebe und der Entwicklung von Folgeerkrankungen bei Kindern? Wir untersuchen diese Fragen in unserem spezialisierten Team aus Biologen, Ernährungswissenschaftlern, Ärzten sowie klinischen und technischen Assistenten. Dabei kombinieren wir Methoden der Grundlagenforschung mit klinischen und genetischen Studien in Kindern und Jugendlichen.

Mehr Informationen zu unseren Projekten finden Sie unter dem Punkt „Research topics“.

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Latest News

  • Now there is mechanistic evidence - also for humans: breastfeeding is the best to do for the baby. As a pediatrician I am really happy to have contributed to this study by Tamás Röszer demonstrating that lipid species in the breast milk preserve energy burning beige adipocytes and can protect against obesity.

  Please find here the full article and the abstract video:

Original publication in J Clin Invest. 2019. https://doi.org/10.1172/JCI125646.

Date: 15.05.2019

  • Dr. Kathrin Landgraf was honored to give a talk at this year's Keystone Symposia Conference "Obesity and Adipose Tissue Biology" in Banff, Alberta, Canada. She presented her work on the obesity susceptibility gene TMEM18 to highly renowned scientists in this field.

      Kathrin Keystone 2019, bearbeitet Plus Symbol

Date: 12.02.2019

  • We published a Letter to our data on "Acceleration of BMI in Early Childhood and Risk of Sustained Obesity" recently appearing in New England Journal of Medicine in response to the comments from Harnois-Leblanc et al. and Ichikawa. Please find the letters here

Date: 28.01.2019

  • Elena Kempf received the Young Scientist Prize 2019 in the category "Obesity" awarded at the Leipzig Research Festival of the Faculty of Medicine and the Faculty of Life Sciences with her work on "Characterization of subcutaneous stromal vascular cells in order to establish new cell models for human adipogenesis".

Date: 18.01.2019

  • Our latest data on the critical age of development of obesity in children are now published in the New England Journal of Medicine. In this large population-based longitudinal study, we show that obesity manifests early in life in children and once present has a very likelihood to persist. The most excessive weight gain occurred early - between 2 and 6 years of age - and subsequently continued at a lower but still constantly positive rate which further worsens obesity.

Find full article including "abstract video" here

Original publication in N Engl J Med 2018; 379:1303-1312; DOI: 10.1056/NEJMoa1803527
See more details/press release here

Date: 04.10.2018

Letzte Änderung: 15.05.2019, 10:48 Uhr
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Klinik und Poliklinik für Kinder- und Jugendmedizin